Mental health is such an important topic that doesn't get enough attention. What is the impact of exercise on mental health? Specifically, what type of exercise can play the most significant role in lowering your mental health risk? Background...
How to live your best life?
learn the latest evidence-based health, nutrition, and wellness research
What is SELF Principle?
SELF Principle is a time tested, evidence-based approach to living your best life based on 4 tenets:

sleep is medicine
Poor sleep is linked to obesity, heart disease, stroke, cancer, and dementia. Aim to sleep 7 or more hours each night
EXERCISE is medicine
Help your heart, mind and body by moving more throughout the day. The journey of a thousand miles beings with the first step!
love is medicine
Show gratitude, make time for family and friends, practice mindfulness, and pass the gift of kindness to others.
food is medicine
You don’t need to follow the latest fad diet. A whole-foods plant based diet is proven to every aspect of your health.

Our mission
SELF Principle is 501c(3) nonprofit that provides
Evidence-based health, nutrition, and wellness research to the public.
Supports children’s education worldwide
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Latest Posts
Plant-based versus Ketogenic diets: What is the evidence?
The field of nutrition is filled with population-based studies. Part of that is because it's incredibly difficult to do a randomized controlled study and to do it long enough to get meaningful results. Thus, the debate over which is the...
Mastering Diabetes with Dr. Cyrus Khambatta: How a plant-based diet can help with Type 1 Diabetes
Cyrus Khambatta, PhD earned a Bachelor of Science in Mechanical Engineering from Stanford University in 2003, then earned a PhD in Nutritional Biochemistry from the University of California at Berkeley in 2012. He is the co-author of many peer-...
High carbohydrate plant-based diet for weight loss?
When it comes to nutrition, there are endless discussions about which macronutrients you should be eating the most or the least. There is always discussion about low-carb, low-fat, high-fat, and high-protein diets. But if we look at the evidence,...
How a single night of not sleeping affects your brain health
Sleep is such an important part of our lives. We spend about one-third of our lives doing it. In fact, if you look at the SELF Principle, sleep is one of the core components. In a US health survey of about 250,000 people, one-third of them...
Diet and Inflammation: What’s the link?
What's the link between diet and inflammation inside the body? We know that inflammation can cause all sorts of problems — everything from belly fat to heart disease, obesity, and cancer. It's also associated with constipation, low energy, high...
Can sleeping extra on weekends make up for sleep loss?
Can sleeping extra on weekends make up for your sleep last that you accrue during the week? What is really the impact of not getting enough sleep on your overall health? Are there any tips and strategies that you can do to improve your sleep...
The amazing benefits of chili peppers
Chili peppers have been shown to have lots of health benefits. What is the link between chili peppers and the risk of heart disease? What is the connection between chili peppers and stroke? How about chili peppers and your cravings for salt? And...
Vegan, healthy lifestyle, COVID-19 vaccine: Interview with Dr. Alex McDonald
Dr. Alex McDonald is a family medicine doctor with a specialization in sports medicine. He focuses on treating the whole person. He is a big believer in exercise, nutrition, and sleep. In this interview, he discusses his approach to fitness,...