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什么是 SELF 原则？ SELF Principle 是一种经过时间考验、以证据为基础的方法，它基于 4 条原则让您过上最美好的生活： 睡眠是良药 运动是良药 爱是良药 食物是药物 Sean Hashmi MD 播放影片 播放影片 32:10 Sean Hashmi MD Life After Ozempic: Impact of stopping GLP-1 Drugs Curious about weight changes after stopping GLP-1 drugs? Let's dive into the evidence on what happens with stopping and how to minimize the risk. References: -Xujia Lu et al. Habitual Coffee, Tea and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity. JCEM, 2024 DOI: 10.1210/clinem/dgae552 -Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022; 24(8): 1553-1564. doi:10.1111/dom.14725 -Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021;325(14):1414–1425. doi:10.1001/jama.2021.3224 -Aronne LJ, et al "Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity" JAMA 2023; DOI: 10.1001/jama.2023.24945. 播放影片 播放影片 38:47 Sean Hashmi MD Gut Health 101: How Your Microbiome Influences Everything! Discover the incredible world of your gut microbiome and its profound impact on your overall health! In this video, we explore how the trillions of bacteria in your gut influence everything from digestion and immunity to mood and mental health. Learn practical tips to nurture a healthy microbiome and unlock the secrets to a healthier, happier you! Join this channel to get access to perks: https://www.youtube.com/channel/UC9LQOhavwlGM58bIWbnXTDA/join If you enjoyed this video and found it informative, please give it a thumbs up. For more insightful content on important health topics, don't forget to subscribe to our channel. 🔔 Subscribe here: https://www.youtube.com/c/SELFPrinciple?sub_confirmation=1 Thank you for your support! FOLLOW US: ✅Website: https://www.selfprinciple.org ✅Instagram: https://www.instagram.com/seanhashmimd ✅Facebook: https://www.facebook.com/SELFPrinciple.org ✅Twitter: https://www.twitter.com/seanhashmimd Medical Disclaimer: The content presented on this channel serves informational purposes only and is not intended to replace individualized medical consultation. We strongly recommend consulting with a qualified healthcare professional for personalized medical advice before initiating any treatment or program. Utilizing any information from this channel is solely at your own risk. The SELF Principle YouTube channel, Podcast, and website are not responsible for any actions taken based on the content provided. Do not disregard or delay seeking professional medical guidance due to information obtained here. #guthealth #gutmicrobiome #healthygut 播放影片 播放影片 35:09 Sean Hashmi MD Healthy Aging: Keto vs. Mediterranean vs. Fasting Discover the Best Diet for Healthy Aging! Are you curious about which diet can help you age gracefully? Let's explore some popular options: 1. Calorie Restriction: This diet focuses on reducing calorie intake without malnutrition. It's known for its potential to extend lifespan and improve overall health. 2. Ketogenic Diet: High in fats and low in carbs, this diet aims to put your body into a state of ketosis, which can help with weight loss and improve brain function. 3. Mediterranean Diet: Rich in fruits, vegetables, whole grains, and healthy fats, this diet is praised for its heart-healthy benefits and anti-inflammatory properties. 4. Intermittent Fasting This eating pattern alternates between periods of fasting and eating. It's known for its potential to improve metabolic health and promote longevity. Which one do you think suits your lifestyle best? Share your thoughts below! #HealthyAging #CalorieRestriction #KetoDiet #MediterraneanDiet #IntermittentFasting #Wellness #HealthyLifestyle #Nutrition #Longevity #AntiAging #HealthTips #FitnessJourney #EatWellLiveWell 播放影片 播放影片 30:46 Sean Hashmi MD The Ultimate Guide to Sleep: Improve Your Health with These Tips! Discover the vital role sleep plays in your overall health and well-being! In this video, we delve into the science behind sleep, its impact on your body and mind, and share practical tips to help you achieve better, more restful nights. Whether you’re struggling with insomnia or just looking to improve your sleep quality, these expert-backed strategies will guide you towards a healthier, more energized life. Don’t miss out on unlocking the power of a good night’s sleep! References: 1. Alvhild Alette Bjørkum, Leandra Griebel, Even Birkeland, Human serum proteomics reveals a molecular signature after one night of sleep deprivation, SLEEP Advances, Volume 5, Issue 1, 2024, zpae042, https://doi.org/10.1093/sleepadvances/zpae042 2. Gardiner C, Weakley J, Burke LM, et al. The effect of caffeine on subsequent sleep: a systematic review and meta-analysis. Sleep Med Rev. 2023;10164. doi:10.1016/j.smrv.2023.101764 3. Emmanuel Frimpong, Melodee Mograss, Tehila Zvionow, Thien Thanh Dang-Vu. The effects of evening high-intensity exercise on sleep in healthy adults: A systematic review and meta-analysis. Sleep Medicine Reviews, 2021; 60: 101535 DOI: 10.1016/j.smrv.2021.101535 4. Afaghi, Ahmad et al. High-glycemic-index carbohydrate meals shorten sleep onset. The American Journal of Clinical Nutrition, Volume 85, Issue 2, 426 - 430 5. Kitamura S, Katayose Y, Nakazaki K, Motomura Y, Oba K, Katsunuma R, Terasawa Y, Enomoto M, Moriguchi Y, Hida A, Mishima K. Estimating individual optimal sleep duration and potential sleep debt. Sci Rep. 2016 Oct 24;6:35812. doi: 10.1038/srep35812. PMID: 27775095; PMCID: PMC5075948. 6. Jean-Philippe Chaput, Caroline Dutil, Ryan Featherstone, Robert Ross, Lora Giangregorio, Travis J. Saunders, Ian Janssen, Veronica J. Poitras, Michelle E. Kho, Amanda Ross-White, Sarah Zankar, and Julie Carrier. 2020. Sleep timing, sleep consistency, and health in adults: a systematic review. Applied Physiology, Nutrition, and Metabolism. 45(10 (Suppl. 2)): S232-S247. https://doi.org/10.1139/apnm-2020-0032 Join this channel to get access to perks: https://www.youtube.com/channel/UC9LQOhavwlGM58bIWbnXTDA/join If you enjoyed this video and found it informative, please give it a thumbs up. For more insightful content on important health topics, don't forget to subscribe to our channel. 🔔 Subscribe here: https://www.youtube.com/c/SELFPrinciple?sub_confirmation=1 Thank you for your support! FOLLOW US: ✅Website: https://www.selfprinciple.org ✅Instagram: https://www.instagram.com/seanhashmimd ✅Facebook: https://www.facebook.com/SELFPrinciple.org ✅Twitter: https://www.twitter.com/seanhashmimd Medical Disclaimer: The content presented on this channel serves informational purposes only and is not intended to replace individualized medical consultation. We strongly recommend consulting with a qualified healthcare professional for personalized medical advice before initiating any treatment or program. Utilizing any information from this channel is solely at your own risk. The SELF Principle YouTube channel, Podcast, and website are not responsible for any actions taken based on the content provided. Do not disregard or delay seeking professional medical guidance due to information obtained here. 播放影片 播放影片 20:04 Sean Hashmi MD Ozempic and Suicidal Ideation: What You Need to Know This week, we explore recent research findings regarding Ozempic (semaglutide) and its association with suicidal thoughts. We’ll delve into an observational study that analyzed a World Health Organization database, revealing a 45% greater rate of reports of suicidal ideation linked to semaglutide compared to other drugs. However, it’s essential to note that this observation doesn’t necessarily imply causality, and the overall occurrence of suicidal thoughts remains low. Join us as we discuss the complexities surrounding GLP-1 drugs and their potential impact on mental health. Reference: Schoretsanitis G, et al "Disproportionality analysis from World Health Organization data on semaglutide, liraglutide, and suicidality" JAMA Netw Open 2024; DOI: 10.1001/jamanetworkopen.2024.23385. Join this channel to get access to perks: https://www.youtube.com/channel/UC9LQOhavwlGM58bIWbnXTDA/join If you enjoyed this video and found it informative, please give it a thumbs up. For more insightful content on important health topics, don't forget to subscribe to our channel. 🔔 Subscribe here: https://www.youtube.com/c/SELFPrinciple?sub_confirmation=1 Thank you for your support! FOLLOW US: ✅Website: https://www.selfprinciple.org ✅Instagram: https://www.instagram.com/seanhashmimd ✅Facebook: https://www.facebook.com/SELFPrinciple.org ✅Twitter: https://www.twitter.com/seanhashmimd Medical Disclaimer: The content presented on this channel serves informational purposes only and is not intended to replace individualized medical consultation. We strongly recommend consulting with a qualified healthcare professional for personalized medical advice before initiating any treatment or program. Utilizing any information from this channel is solely at your own risk. The SELF Principle YouTube channel, Podcast, and website are not responsible for any actions taken based on the content provided. Do not disregard or delay seeking professional medical guidance due to information obtained here. 播放影片 播放影片 31:27 Sean Hashmi MD Higher Protein linked to lower Mortality in Kidney Disease? In a new study published in JAMA Network Open, researchers investigated the impact of protein intake on all-cause mortality among older adults with chronic kidney disease (CKD). Here are the key findings: Risk Reduction with Higher Protein Intake: Among 8543 adults aged 60 years and older, those with higher total protein intake experienced significant risk reductions for all-cause mortality over a 10-year period. The risk reductions were as follows: 12% lower risk for CKD patients with protein intakes of 1.0 g/kg/d 21% lower risk for protein intakes of 1.2 g/kg/d 27% lower risk for protein intakes of 1.4 g/kg/d 33% lower risk for protein intakes of 1.6 g/kg/d Compared to a reference intake of 0.8 g/kg/d. Incremental Benefits: Each 0.2 g/kg/d increase in total protein intake was associated with an 8% lower risk of death in the CKD group. In the group without CKD, the risk reduction was even more pronounced at 15%. Age-Specific Effects: For adults aged 75 years and older, every 0.2 g/kg/d increase in total protein intake correlated with a 9% lower risk of all-cause mortality. Interestingly, younger adults (under 75 years) did not exhibit a significant survival advantage. Carballo-Casla A, Avesani CM, Beridze G, et al. Protein intake and mortality in older adults with chronic kidney disease. JAMA Netw Open. Published online August 7, 2024. doi:10.1001/jamanetworkopen.2024.26577 Join this channel to get access to perks: https://www.youtube.com/channel/UC9LQOhavwlGM58bIWbnXTDA/join If you enjoyed this video and found it informative, please give it a thumbs up. For more insightful content on important health topics, don't forget to subscribe to our channel. 🔔 Subscribe here: https://www.youtube.com/c/SELFPrinciple?sub_confirmation=1 Thank you for your support! FOLLOW US: ✅Website: https://www.selfprinciple.org ✅Instagram: https://www.instagram.com/seanhashmimd ✅Facebook: https://www.facebook.com/SELFPrinciple.org ✅Twitter: https://www.twitter.com/seanhashmimd Medical Disclaimer: The content presented on this channel serves informational purposes only and is not intended to replace individualized medical consultation. We strongly recommend consulting with a qualified healthcare professional for personalized medical advice before initiating any treatment or program. Utilizing any information from this channel is solely at your own risk. The SELF Principle YouTube channel, Podcast, and website are not responsible for any actions taken based on the content provided. Do not disregard or delay seeking professional medical guidance due to information obtained here. 最新消息 此語言尚未有已發佈之文章 文章發佈後將於此處顯示。 阅读更多 加入我们 支持我们的研究和教育使命 现在捐款

关于 它点燃了我姐姐和我的健康，当我看到营养和生活方式如何改善亲人的生活时，它被点燃了。今天，我提供基于证据的健康、营养和保健研究和信息，以帮助每个人过上最美好的生活。此外，我和我的团队通过学校用品、奖学金等方式支持全球儿童教育。 ​ 我们董事会的每一位成员都自愿为此付出时间和金钱。 SELF Principle 是为数不多的非营利组织之一，您捐出的每一美元都直接用于帮助有需要的儿童。与其他 501(c)(3) 组织不同，董事会自掏腰包支付非营利组织的行政费用。我们还“脚踏实地”，为美国和世界各地的低收入儿童提供他们取得成功所需的教育用品。 ​ 带着感激之情， ​ 肖恩·哈希米 (Sean Hashmi)，医学博士，理学硕士，FASN 我们的任务 通过以易于访问的格式提供有关健康、营养、健身和健康的最新循证研究来改善健康状况。 我们的愿景 成为所有人值得信赖的健康、健身、营养和保健信息来源。 My Story Have you ever felt that there must be something more to life? A missing piece that you just can't seem to find? For me, that missing piece was the opportunity to make a real impact in the world and serve others. I've been blessed with so much in my life, and I knew it was time to give back. ​ It all started during my childhood in Pakistan. I fell ill with a severe case of measles that left me bedridden for months. Doctors told my parents that I wouldn't survive, but somehow I did. However, my health and digestive issues continued to plague me for years to come, and my experiences with doctors and healthcare ignited a spark inside me. ​ That spark was fanned into a flame when, at the age of ten, my family moved to the United States. We struggled to make ends meet, and my older sister's epilepsy made life even more challenging. One night, she had a seizure in her sleep, and I tried my best to save her, but I couldn't. The tragic loss of my sister led me to make a promise to become a doctor and help others in need. ​ After obtaining my medical degree and marrying my soulmate, we wanted to start a family, but my wife's pulmonary hypertension and lupus made it difficult. I was determined to find the right nutrition and lifestyle habits to help her manage her illness and regain control of her health. It took years of trying and heartache, but we now have two beautiful daughters, and our family is stronger and more grateful than ever. ​ That's why I founded SELF Principle - to share my knowledge and help others live their best lives. My life's mission is to serve and make a difference in this world, and I'm so grateful for the opportunity to give back. Our Mission 我们今天需要您的支持！ 捐

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